saberhq.com / sidechain
Virtual Cell Challenge · 2026

Sidechain.

This is a fun project where I’m the only human in the loop of a multi-agent research workflow powered by Claude — a solo-team entry to VCC26, building robust models that predict how a cell’s transcriptome shifts when a gene is silenced. This website documents our journey in public.

Chasing top 10% for the fun of it ;)
top 10%
Best · gap to top 100
0.2226·0.0485
SER-29abefhkrswx · rank 100 at 0.2711
Latest
0.2226 +0.0351
SER-29abefhkrswx · #207 of 1635

Every submission, as Arc scored it. The live board shows only a team's latest entry, so a name opens the rank that entry held when it was scored, and the models page says what each model tried and what its name means.

Overall score · 0 = the context mean, 1 = a biological replicate
00.10.20.3
SER-29abefhkrswx 0.2226
SER-28abefhkrswx 0.1875
SER-27abefhkrswx 0.1875
SER-21aefhkrswx 0.1757
SER-19aefhkrsw 0.1684
SER-17aefhkrsw 0.1657
SER-14aefksw 0.1626
SER-13aefknw 0.1360
SER-12aefkw 0.1438
SER-11abefknw 0.1360
SER-10abefnw 0.1353
SER-9abefkn 0.1144
SER-7abefn 0.1131
SER-6aefn 0.1091
SER-5acfnt 0.1075
SER-4afn 0.1078
SER-3afn 0.1071
SER-3afgn 0.0992
SER-3fn 0.1034
SER-3n 0.0963
SER-2 0.0937
SER-1n 0.0822
SER-1p 0.0730
SER-1 0.0788
Calibration runs · what this means →
SER-20aefhkrsw 0.1673
SER-18aefksvw 0.1612
SER-16aefhkrsw 0.1423
SER-15aefkrsw below zero · off this scale −0.0039
SER-8abefkn 0.1132
PHE-2 below zero · off this scale −0.9807